Asymmetric synthesis of 3-spirocyclopropyl-2-oxindoles via intramolecular trapping of chiral aza-ortho-xylylene.
نویسندگان
چکیده
Chiral aza-ortho-xylylene intermediates were efficiently generated from 3-chloro-3-substituted oxindole precursors. The first intramolecular trapping of chiral aza-ortho-xylylene intermediates led to a highly asymmetric synthesis of 3-spirocyclopropyl-2-oxindoles.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 80 شماره
صفحات -
تاریخ انتشار 2013